Today my guests Amy and Anthony from Great Britain did a run from Casa de Kathy in Esperanza to Isabel II. They loved it and took a public van back to Esperanza. I tried to talk them out of it but Amy explained she had run/biked/kayaked across the entire width of Costa Rica! So off they went and were back home in about an hour and a half.
Running is best done early in the morning to avoid the heat. Only you know your limits and capabilities!